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Article

IDH1 mutation is associated with improved resection rates, progression-free survival and overall survival in patients with anaplastic astrocytomas.

Journal of neuro-oncology - 1 Sept 2024

Ahmeti Hajrullah, Kiese Daniel, Freitag-Wolf Sandra, Kalab Michael, Röcken Christoph, Jansen Olav, Mehdorn Maximilian H, Synowitz Michael

Abstract excerpt

PURPOSE: The introduction of molecular markers in to the diagnosis of gliomas has changed the therapeutic approach to this tumors. The aim of this study was to examine the impact of surgery on anaplastic astrocytomas (AA), which has not previously been fully elucidated. METHODS: This was a retrospective study involving a total of 143 patients who underwent surgery for primary AA in our department between 1995 and...

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PMID: 38909340
DOI: 10.1007/s11060-024-04743-x

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