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Confined placental mosaicism and the association with pregnancy outcome and fetal growth: a review of the literature

15 Feb 2021

Abstract excerpt

BACKGROUND: Chromosomal mosaicism can be detected in different stages of early life: in cleavage stage embryos, in blastocysts and biopsied cells from blastocysts during preimplantation genetic testing for aneuploidies (PGT-A) and later during prenatal testing, as well as after birth in cord blood. Mosaicism at all different stages can be associated with adverse pregnancy outcomes. There is an onward discussion...

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PMID: 33984128
DOI: 10.1093/humupd/dmab009

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