Article
40 years of researching the Del phenotype results in a change of transfusion practice.
Transfusion - 1 Jul 2024
Flegel Willy Albert, Srivastava Kshitij
Abstract excerpt
Anti-D cannot agglutinate red cells of any Del phenotype in routine serology. Many individuals with East Asian ancestry who type D-negative in serology harbor a Del phenotype. Almost all such individuals carry one distinct DEL variant, dubbed Asian-type DEL, known as RHD*01EL.01, RHD*DEL1, RHD:c.1227G>A, formerly known as RHD(K409K). Clinical evidence strongly suggests that Asian-type DEL individuals can safely...
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