Article
Primary anti-D immunization by DEL red blood cells.
The Korean journal of laboratory medicine - 1 Aug 2009
Kim Kyeong-Hee, Kim Kyung-Eun, Woo Kwang-Sook, Han Jin-Yeong, Kim Jeong-Man, Park Kyoung Un
Abstract excerpt
Extremely weak D variants called DEL are serologically detectable only by adsorption-elution techniques. A nucleotide change of exon 9 in RHD gene, RHD (K409K, 1227G>A) allelic variant is present in almost all the DEL individuals of East Asians. No DEL phenotype has yet been shown to induce a primary alloanti-D immunization in East Asia. A 68-yr-old D-negative Korean man was negative for anti-D at admission, and...
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