Article
Genetics of hypertrophic cardiomyopathy.
Current opinion in cardiology - 1 May 2010
Konno Tetsuo, Chang Stephen, Seidman Jonathan G, Seidman Christine E
Abstract excerpt
PURPOSE OF REVIEW: Hypertrophic cardiomyopathy (HCM), the most common inherited cardiac disorder, exhibits remarkable genetic and clinical heterogeneity. This manuscript reviews recent discoveries of disease-causing genes and their clinical consequences, and provides an overview of research that aims to elucidate how HCM ensues from a single-nucleotide mutation. RECENT FINDINGS: The spectrum of genes that are...
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