Article
Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum.
PLoS genetics - 1 Jun 2024
Kimball Abigail, Funkhouser-Jones Lisa, Huang Wanyi, Xu Rui, Witola William H, Sibley L David
Abstract excerpt
Very little is known about the process of meiosis in the apicomplexan parasite Cryptosporidium despite the essentiality of sex in its life cycle. Most cell lines only support asexual growth of Cryptosporidium parvum (C. parvum), but stem cell derived intestinal epithelial cells grown under air-liquid interface (ALI) conditions support the sexual cycle. To examine chromosomal dynamics during meiosis in C. parvum,...
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