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Article

Investigation of somatic NKX2-5, GATA4 and HAND1 mutations in patients with tetralogy of Fallot.

Pathology - 1 Jun 2011

Wang Jian, Lu Yanan, Chen Huiwen, Yin Minzhi, Yu Tingting, Fu Qihua

Abstract excerpt

AIMS: Tetralogy of Fallot (TOF) is the most common type of congenital heart disease (CHD). Several genes essential for heart development have been identified. In recent years, there have been a few reports of the high frequency of somatic mutation in the heart tissues of CHD patients. The majority of findings were reported by the same investigators using formalin fixed tissues. In this study, we investigate the...

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Source

Identifiers

PMID: 21519287
DOI: 10.1097/PAT.0b013e32834635a9

Genes

GATA4
HAND1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Investigation of somatic NKX2-5, GATA4 and HAND1 mutations in patients with tetralogy of Fallot.PMID 21519287Read ↗

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