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Article

Associations of cholecystectomy with the risk of gastroesophageal reflux disease: a Mendelian randomization study.

International journal of surgery (London, England) - 1 Oct 2024

Qian Jin, Xu Huawei, Liu Jun, Zheng Yihu

Abstract excerpt

BACKGROUND: Cholecystectomy is the standard surgery for patients with gallbladder disease, but the impact of cholecystectomy on gastroesophageal reflux disease (GERD) is not clear. METHODS: The authors obtained genetic variants associated with cholecystectomy at a genome-wide significant level ( P -value <5×10 -8 ) as instrumental variables (IVs) and performed Mendelian randomization to explore the relationship...

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Identifiers

PMID: 38869973
DOI: 10.1097/JS9.0000000000001806
PMCID: PMC11487017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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