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Article

Exploring the correlation among genetic variants, cholecystectomy and gut microbiome: A Mendelian randomization study.

Medicine - 27 Sept 2024

Yin Yulai, Zhang Xiaoyu

Abstract excerpt

This Mendelian randomization (MR) study aims to explore the relationship between gut microbiota and the occurrence of cholelithiasis, as well as the impact of cholecystectomy on the gut microbiota. This study leverages data on exposures and outcomes from the GWAS database, employing the inverse variance weighting (IVW) method to obtain primary causal estimates. Heterogeneity is assessed using Cochran Q and Rücker...

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Identifiers

PMID: 39331944
DOI: 10.1097/MD.0000000000039852
PMCID: PMC11441970

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