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Article

Associations of cholecystectomy with the risk of colorectal cancer: a Mendelian randomization study.

Chinese medical journal - 5 Apr 2023

Chen Lanlan, Fan Zhongqi, Sun Xiaodong, Qiu Wei, Mu Wentao, Chai Kaiyuan, Cao Yannan, Wang Guangyi, Lv Guoyue

Abstract excerpt

BACKGROUND: Cholecystectomy is a standard surgery for patients suffering from gallbladder diseases, while the causal effects of cholecystectomy on colorectal cancer (CRC) and other complications are still unknown. METHODS: We obtained genetic variants associated with cholecystectomy at a genome-wide significant level ( P value <5 × 10 -8 ) as instrumental variables (IVs) and performed Mendelian randomization (MR)...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37027252
DOI: 10.1097/CM9.0000000000002612
PMCID: PMC10150870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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