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A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery

30 May 2021

Abstract excerpt

Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic, bat-borne paramyxoviruses in the genus Henipavirus that cause severe and often fatal acute respiratory and/or neurologic diseases in humans and livestock. There are currently no approved antiviral therapeutics or vaccines for use in humans to treat or prevent NiV or HeV infection. To facilitate development of henipavirus antivirals, a high-throughput...

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PMID: 34077807
DOI: 10.1016/j.antiviral.2021.105084

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