Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel MYC-ZNF706-SLC7A11 regulatory circuit contributes to cancer progression and redox balance in human hepatocellular carcinoma

11 Jun 2024

Abstract excerpt

The oncogenic potential of chromosome 8q22 copy number gain in liver cancer remains to be depicted. Here, we report that ZNF706, encoded by a gene mapped to chromosome 8q22, is a C2H2-type zinc finger protein. However, the biological function and mechanism of ZNF706 have been poorly investigated. Clinically, ZNF706 expression was elevated in hepatocellular carcinoma (HCC), and high ZNF706 expression was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38862581
DOI: 10.1038/s41418-024-01324-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel MYC-ZNF706-SLC7A11 regulatory circuit contributes to cancer progression and redox balance in human hepatocellular carcinomaPMID 38862581Read ↗

ZC3H13 reduced DUOX1-mediated ferroptosis in laryngeal squamous cell carcinoma cells through m6A-dependent modificationSemantic proximity Read ↗

FSP1: a key regulator of ferroptosisSemantic proximity Read ↗

Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosisSemantic proximity Read ↗

The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker valueSemantic proximity Read ↗

Zinc finger protein 296 promotes hepatocellular carcinoma progression via inducing interaction between macrophages and B cellsSemantic proximity Read ↗

Identification of key iron metabolism-related long non-coding RNAs in hepatocellular carcinoma based on bioinformatics analysisSemantic proximity Read ↗

Suppression of SLC39A6‐CREB1 axis in liver cancer causes PCK1 ‐mediated mitochondrial dysfunctionSemantic proximity Read ↗

CircRNF10 triggers a positive feedback loop to facilitate progression of glioblastoma via redeploying the ferroptosis defense in GSCsSemantic proximity Read ↗

The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular CarcinomaSemantic proximity Read ↗

SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinomaSemantic proximity Read ↗

The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study.Semantic proximity Read ↗

Integrated functional genomics-identified LYRM4 promotes fumarate accumulation and hepatocellular carcinoma progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.