Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIM-3 transcriptomic landscape with clinical and immunomic correlates in cancer

1 Jan 2024

Abstract excerpt

percentile) levels. High TIM-3 expression independently and significantly correlated with high PD-L2 RNA expression (odds ratio (OR) 9.63, 95% confidence interval (CI) 4.91-19.4, P<0.001) and high VISTA RNA expression (OR 2.71, 95% CI 1.43-5.13, P=0.002), all in multivariate analysis. High TIM-3 RNA did not correlate with overall survival (OS) from time of metastatic disease in the 272 patients who never received...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Macrophage Migration Inhibitory Factor
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38859842
DOI: 10.62347/mqff6404

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIM-3 transcriptomic landscape with clinical and immunomic correlates in cancerPMID 38859842Read ↗

Pan‐cancer analysis of TIM ‐3 transcriptomic expression reveals high levels in pancreatic cancer and interpatient heterogeneitySemantic proximity Read ↗

Viewing the immune checkpoint VISTA: landscape and outcomes across cancersSemantic proximity Read ↗

PD-1 transcriptomic landscape across cancers and implications for immune checkpoint blockade outcomeSemantic proximity Read ↗

LAG ‐3 transcriptomic expression patterns across malignancies: Implications for precision immunotherapeuticsSemantic proximity Read ↗

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneitySemantic proximity Read ↗

Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapiesSemantic proximity Read ↗

Transcriptomic Profiling of Tumor-Infiltrating CD4+TIM-3+ T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer PatientsSemantic proximity Read ↗

Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy.Semantic proximity Read ↗

PD-1/LAG-3 Dysfunctionality Signatures in Human CancersSemantic proximity Read ↗

Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome.Semantic proximity Read ↗

TIM3 <sup>+</sup> Tumor Associated M2 Macrophages Impair Antitumor T Cell Immunity and Promote Gastric Cancer Progression and Peritoneal MetastasisSemantic proximity Read ↗

Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer ExplantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.