An HLA-B7-specific antibody in an HLA-B*07 positive patient explained by a nonexpressed allele (HLA-B*07:181N).

doi:10.1111/tan.13045

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Article

An HLA-B7-specific antibody in an HLA-B07 positive patient explained by a nonexpressed allele (HLA-B07:181N).

HLA - 1 Jul 2017

Wenda S, Faé I, Fischer G F

Abstract excerpt

Antibody identification by a bead array assay in a kidney patient revealed several HLA-specific antibodies including one directed against the HLA-B7 antigen. Low-resolution typing of the patient indicated the presence of an HLA-B*07 allele. To rule out an HLA-specific autoantibody the HLA-typing of the patient was further refined by nucleotide sequencing on a next-generation sequencing platform and eventually...

Topics

Adult
Alleles
Base Sequence
Female
Gene Expression
Genotype
HLA-B39 Antigen
HLA-B7 Antigen
High-Throughput Nucleotide Sequencing
Histocompatibility Testing
Humans
Isoantibodies
Kidney Transplantation
Polymerase Chain Reaction
Protein Isoforms
Sequence Alignment
Sequence Analysis, DNA
Tissue Donors

Source

Open in PubMed

Identifiers

PMID: 28417556
DOI: 10.1111/tan.13045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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