Article
Genetic alterations in the pmrAB two-component system and lipid A biosynthesis genes of polymyxin-resistant Acinetobacter baumannii isolates.
Acta microbiologica et immunologica Hungarica - 2 Jul 2024
El Mrimar Nadia, Belouad El Mehdi, Benaissa Elmostafa, Bssaibis Fatna, Jazouli Mohammed, El Alaoui My Abdelaziz, Maleb Adil, Elouennass Mostafa
Abstract excerpt
The rate of pandrug-resistant Acinetobacter baumannii strains is on the rise in all continents. This bacterium can acquire resistance to all antibiotics, even to colistin. Alterations in the lipid A or/and the two-component pmrAB were earlier detected in colistin resistance. We investigated and analyzed two strains of A. baumannii (ABRC1 and ABRC2) isolated from two patients admitted to intensive care unit with a...
Topics
- Acinetobacter baumannii
- Humans
- Lipid A
- Bacterial Proteins
- Anti-Bacterial Agents
- Acinetobacter Infections
- Microbial Sensitivity Tests
- Drug Resistance, Bacterial
- Polymyxins