Article
A novel type of three band pattern at STR loci.
Forensic science international. Genetics - 1 Jul 2024
Rolf B, Phillip A, Hannig K, Köhler S, Göttesdorfer I
Abstract excerpt
SE33 or ACTBP2 is the most polymorphic locus in many national DNA databases and in the commercial STR kits used to type both crime scene samples and reference samples to populate these databases. We describe the molecular reason for a three band pattern of SE33 seen in several samples. A SNP in the flanking SE33 region causes the binding of the unlabelled D3S1358 primer. As a result, a "chimeric" PCR product of...
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