Article
The John Charnley Award: The Impact of Human Leukocyte Antigen Genotype on Bacterial Infection Rates and Successful Eradication in Total Hip Arthroplasty.
The Journal of arthroplasty - 1 Sept 2024
Neufeld Michael E, Sheridan Gerard A, MacDonell Tanya, Howard Lisa C, Masri Bassam A, Keown Paul, Sherwood Karen, Garbuz Donald S
Abstract excerpt
BACKGROUND: Genetics play an important role in several medical domains; however, the influence of human leukocyte antigen (HLA) genotype on the development of periprosthetic joint infection (PJI) in total hip arthroplasty (THA) remains unknown. The primary aim of this study was to determine if HLA genotype is associated with the development of bacterial PJI in THA. Secondarily, we evaluated the association...
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