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Chemotherapy for patients with EGFR-mutated NSCLC after progression on EGFR-TKI's: Exploration of efficacy of unselected treatment in a multicenter cohort study.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2023

Steendam Christi M J, Ernst Sophie M, Badrising Sushil K, Paats Marthe S, Aerts Joachim G J V, de Langen Adrianus J, Dingemans Anne-Marie C

Abstract excerpt

OBJECTIVES: In patients with Epidermal Growth Factor Receptor (EGFR)-mutated non-small cell lung (NSCLC) chemotherapy remains standard of care after progression on EGFR-tyrosine kinase inhibitors (TKIs). With the development of anti-angiogenic agents and immune checkpoint inhibitors the landscape of systemic regimens has changed significantly. This cohort study aims to evaluate the efficacy of chemotherapy...

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PMID: 37216839
DOI: 10.1016/j.lungcan.2023.107248

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