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Dolutegravir induces FOLR1 expression during brain organoid development

17 May 2024

Abstract excerpt

During the first month of pregnancy, the brain and spinal cord are formed through a process called neurulation. However, this process can be altered by low serum levels of folic acid, environmental factors, or genetic predispositions. In 2018, a surveillance study in Botswana, a country with a high incidence of human immunodeficiency virus (HIV) and lacking mandatory food folate fortification programs, found that...

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PMID: 38828282
DOI: 10.3389/fnmol.2024.1394058

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