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Article

Causal relationship between ulcerative colitis and male infertility: A two-sample Mendelian randomization study.

PloS one - 1 Jan 2024

Wang Xia, Li Tongyi, Chen Qiu

Abstract excerpt

AIMS: To explore the causal relationship between ulcerative colitis (UC) and male infertility using Mendelian randomization method with single nucleotide polymorphism (SNP) as the instrumental variables. METHODS: Genetic loci closely associated with UC were extracted as instrumental variables and male infertility was the outcome variable in pooled data from the gene-wide association study (GWAS),which was derived...

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Share to Colitis, Ulcerative
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infertility, Male

Share to Inflammatory Bowel Disease

Share to Linkage Disequilibrium

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 38814907
DOI: 10.1371/journal.pone.0303827
PMCID: PMC11139326

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