Dietary mercury intake, the IL23R rs10889677 polymorphism, and the risk of gastric cancer in a Korean population: a hospital-based case-control study.

doi:10.4178/epih.e2024051

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Dietary mercury intake, the IL23R rs10889677 polymorphism, and the risk of gastric cancer in a Korean population: a hospital-based case-control study.

Epidemiology and health - 1 Jan 2024

Kim Ji Hyun, Gunathilake Madhawa, Lee Jeonghee, Choi Il Ju, Kim Young-Il, Kim Jeongseon

Abstract excerpt

OBJECTIVES: Mercury can stimulate immune responses through T helper 17 (Th17). The gene IL23R is a key factor in Th17 function, which may also contribute to digestive tract diseases. The aim of this study was to identify the associations between dietary mercury and gastric cancer (GC) and to investigate whether the IL23R rs10889677 polymorphism modifies those associations. METHODS: This case-control study...

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PMID: 38810984
DOI: 10.4178/epih.e2024051
PMCID: PMC11573488

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