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Article

Diagnosis and prognosis models for hepatocellular carcinoma patient's management based on tumor mutation burden.

Journal of advanced research - 1 Nov 2021

Tang Bufu, Zhu Jinyu, Zhao Zhongwei, Lu Chenying, Liu Siyu, Fang Shiji, Zheng Liyun, Zhang Nannan, Chen Minjiang, Xu Min, Yu Risheng, Ji Jiansong

Abstract excerpt

Introduction: The development and prognosis of HCC involve complex molecular mechanisms, which affect the effectiveness of its treatment strategies. Tumor mutational burden (TMB) is related to the efficacy of immunotherapy, but the prognostic role of TMB-related genes in HCC has not yet been determined clearly. Objectives: In this study, we identified TMB-specific genes with good prognostic value to build...

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Share to Cancer Immunotherapy and Biomarkers
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferroptosis and cancer prognosis

Share to Gene Expression Regulation, Neoplastic

Share to Immune cells in cancer

Share to Liver Neoplasms

Share to Mutation

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Source

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Identifiers

PMID: 34603786
DOI: 10.1016/j.jare.2021.01.018
PMCID: PMC8463909

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