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Article

Myocardial contractility characteristics of hypertrophic cardiomyopathy patients with and without sarcomere mutation.

Heart and vessels - 1 Nov 2024

Zhang Juan, Li Jing, Wang Bo, Wang Jing, Hu Rui, Shan Bo, Han Yupeng, Zhao Xueli, Zhang Jun, Zhang Yanmin, Ta Shengjun, Liu Liwen

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) patients with sarcomere mutations have an increased risk of heart failure and left ventricular (LV) systolic dysfunction. We hypothesize that sarcomere mutation carriers have abnormal myocardial contractility before LV dysfunction. Therefore, we aimed to associate myocardial contractility with identified sarcomere mutations and predict genotyped HCM patients with sarcomere...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38806839
DOI: 10.1007/s00380-024-02414-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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