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Article

Identifying widespread and recurrent variants of genetic parts to improve annotation of engineered DNA sequences.

PloS one - 1 Jan 2024

McGuffie Matthew J, Barrick Jeffrey E

Abstract excerpt

Engineered plasmids have been workhorses of recombinant DNA technology for nearly half a century. Plasmids are used to clone DNA sequences encoding new genetic parts and to reprogram cells by combining these parts in new ways. Historically, many genetic parts on plasmids were copied and reused without routinely checking their DNA sequences. With the widespread use of high-throughput DNA sequencing technologies,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38805426
DOI: 10.1371/journal.pone.0304164
PMCID: PMC11132462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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