Article
Phenotypic assessment of antiviral activity for spiro-annulated oxepanes and azepenes.
Chemical biology & drug design - 1 May 2024
Osolodkin Dmitry I, Kozlovskaya Liubov I, Iusupov Ildar R, Kurkin Alexander V, Shustova Elena Y, Orlov Alexey A, Khvatov Evgeny V, Mutnykh Elena S, Kurashova Svetlana S, Vetrova Anna N, Yatsenko Darya O, Goryashchenko Alexander S, Ivanov Vladimir N, Lukyanenko Evgeny R, Karpova Evgenia V, Stepanova Daria A, Volok Viktor P, Sotskova Svetlana E, Dzagurova Tamara K, Karganova Galina G, Lukashev Alexander N, Ishmukhametov Aydar A
Abstract excerpt
Evolutionary potential of viruses can result in outbreaks of well-known viruses and emergence of novel ones. Pharmacological methods of intervening the reproduction of various less popular, but not less important viruses are not available, as well as the spectrum of antiviral activity for most known compounds. In the framework of chemical biology paradigm, characterization of antiviral activity spectrum of new...
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