Article

HIV-1 RNA in Large and Small Plasmatic Extracellular Vesicles: a Novel Parameter for Monitoring Immune Activation and Virological Failure

2024-11-04

Abstract excerpt

<h4>Background</h4> Antiretroviral therapy (ART) suppresses viral replication in most people living with HIV-1 (PLWH). However, PLWH remain at risk of viral rebound. HIV-1 infection modifies the content of extracellular vesicles (EVs). The changes in microRNA content in EVs are biomarkers of immune activation and viral replication in PLWH. Moreover, viral molecules are enclosed in EVs produced from infected cells....

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Literature Corpus work: a27b73c6-72c8-5770-9c70-4b6dd44ca1f9
DOI: 10.1101/2024.11.01.24316593

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