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Analytical and Clinical Validation of a Target-Enhanced Whole Genome Sequencing-Based Comprehensive Genomic Profiling Test.

Cancer investigation - 1 May 2024

Ferguson Stephanie, Sriram Shruthi, Wallace Jonathan Kyle, Lee Jeonghoon, Kim Jung-Ah, Lee Yoonsuh, Oh Brian Baek-Lok, Lee Won Chul, Lee Sangmoon, Connolly-Strong Erin

Abstract excerpt

Evaluation of the test performance of the Target enhanced whole-genome sequencing (TE-WGS) assay for comprehensive oncology genomic profiling. The analytical validation of the assay included sensitivity and specificity for single nucleotide variants (SNVs), insertions/deletions (indels), and structural variants (SVs), revealing a revealed a sensitivity of 99.8% for SNVs and 99.2% for indels. The positive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38773925
DOI: 10.1080/07357907.2024.2352438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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