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Article

Association between Psoriasis and MTHFR polymorphisms: a systematic review and meta-analysis.

Archives of dermatological research - 21 May 2024

Matsuo Rika, Haught Katrina, Guo William, Na Sean, Lu Kimberly, Kaufmann Tara, Siamas Katherine

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is key to the metabolism of folic acid, with loss of function mutations resulting in elevated homocysteine levels, a known risk factor for cardiovascular disease. Psoriasis patients may demonstrate hyperhomocysteinemia. To assess for the association between psoriasis and MTHFR C677T and A1298C polymorphisms. A systematic literature search was conducted in MEDLINE,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38771513
DOI: 10.1007/s00403-024-02905-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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