Article
Interaction of MTHFR gene with smoking and alcohol use and haplotype combination susceptibility to psoriasis in Chinese population.
Immunologic research - 1 Aug 2018
Luo Quan, Zeng Jingxin, Li Wei, Lin Ling, Zhou Xin, Tian Xin, Liu Weiyu, Zhang Lidan, Zhang Xibao
Abstract excerpt
To investigate the association of MTHFR gene polymorphism and additional gene-gene interaction with psoriasis risk. GMDR model was used to screen the best gene-smoking and gene-drinking interaction combinations. Logistic regression was performed to investigate association between two SNPs and psoriasis. For psoriasis patient-control haplotype analyses, the SHEsis online haplotype analysis software (...
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