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Transcriptomic profiling and regulatory pathways of cardiac resident macrophages in aging

20 May 2024

Abstract excerpt

Abstract Cardiovascular diseases are an array of age-related disorders, and accumulating evidence suggests a link between cardiac resident macrophages (CRMs) and the age-related disorders. However, how does CRMs alter with aging remains elusive. In the present study, aged mice (20 months old) have been employed to check for their cardiac structural and functional alterations, and the changes in the proportion of...

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PMID: 38763956
DOI: 10.1007/s00018-024-05235-x

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