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Article

Circulating microRNA profile of long-lived Okinawans identifies novel potential targets for optimizing lifespan and health span.

Aging cell - 1 Aug 2024

Noureddine Sarah, Schneider Augusto, Strader Sydney, Zhu Xiang, Dhahbi Joseph, Allsopp Richard, Willcox D Craig, Donlon Timothy A, Shimabukuro Michio, Higa Moritake, Suzuki Makoto, Torigoe Trevor, Ashiqueali Sarah, Yadav Hariom, Willcox Bradley J, Masternak Michal M

Abstract excerpt

Nonagenarians and centenarians serve as successful examples of aging and extended longevity, showcasing robust regulation of biological mechanisms and homeostasis. Given that human longevity is a complex field of study that navigates molecular and biological mechanisms influencing aging, we hypothesized that microRNAs, a class of small noncoding RNAs implicated in regulating gene expression at the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38751007
DOI: 10.1111/acel.14191
PMCID: PMC11320357

Genes

FOXO3

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