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Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders.

Biology of sex differences - 15 May 2024

Matte Bon Gloria, Kraft Dominik, Comasco Erika, Derntl Birgit, Kaufmann Tobias

Abstract excerpt

BACKGROUND: Sex differences exist in the prevalence and clinical manifestation of several mental disorders, suggesting that sex-specific brain phenotypes may play key roles. Previous research used machine learning models to classify sex from imaging data of the whole brain and studied the association of class probabilities with mental health, potentially overlooking regional specific characteristics. METHODS: We...

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Identifiers

PMID: 38750598
DOI: 10.1186/s13293-024-00615-1
PMCID: PMC11097569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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