Article
Mapping the Multiscale Proteomic Organization of Cellular and Disease Phenotypes.
Annual review of biomedical data science - 1 Aug 2024
Cesnik Anthony, Schaffer Leah V, Gaur Ishan, Jain Mayank, Ideker Trey, Lundberg Emma
Abstract excerpt
While the primary sequences of human proteins have been cataloged for over a decade, determining how these are organized into a dynamic collection of multiprotein assemblies, with structures and functions spanning biological scales, is an ongoing venture. Systematic and data-driven analyses of these higher-order structures are emerging, facilitating the discovery and understanding of cellular phenotypes. At...
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