Article
Functional and biochemical characterisation of remote homologues of type IV pili proteins PilN and PilO in Helicobacter pylori.
IUBMB life - 1 Oct 2024
Bonny Sharmin Q, Zhou Xiaotian, Khan Mohammad F, Rahman Mohammad M, Xin Yue, Vankadari Naveen, Tikhomirova Alexandra, Homman-Ludiye Jihane, Roujeinikova Anna
Abstract excerpt
Helicobacter pylori encodes homologues of PilM, PilN and PilO from bacteria with Type IV pili, where these proteins form a pilus alignment complex. Inactivation of pilO changes H. pylori motility in semi-solid media, suggesting a link to the chemosensory pathways or flagellar motor. Here, we showed that mutation of the pilO or pilN gene in H. pylori strain SS1 reduced the mean linear swimming speed in liquid...
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