Article
PRIEST: predicting viral mutations with immune escape capability of SARS-CoV-2 using temporal evolutionary information.
Briefings in bioinformatics - 27 Mar 2024
Saha Gourab, Sawmya Shashata, Saha Arpita, Akil Md Ajwad, Tasnim Sadia, Rahman Md Saifur, Rahman M Sohel
Abstract excerpt
The dynamic evolution of the severe acute respiratory syndrome coronavirus 2 virus is primarily driven by mutations in its genetic sequence, culminating in the emergence of variants with increased capability to evade host immune responses. Accurate prediction of such mutations is fundamental in mitigating pandemic spread and developing effective control measures. This study introduces a robust and interpretable...
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