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Article

Two distinct mechanisms of Plexin A function in Drosophila optic lobe lamination and morphogenesis.

Development (Cambridge, England) - 15 May 2024

Bustillo Maria E, Douthit Jessica, Astigarraga Sergio, Treisman Jessica E

Abstract excerpt

Visual circuit development is characterized by subdivision of neuropils into layers that house distinct sets of synaptic connections. We find that, in the Drosophila medulla, this layered organization depends on the axon guidance regulator Plexin A. In Plexin A null mutants, synaptic layers of the medulla neuropil and arborizations of individual neurons are wider and less distinct than in controls. Analysis of...

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Source

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Identifiers

PMID: 38738602
DOI: 10.1242/dev.202237
PMCID: PMC11190435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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