Article
Mesencephalic astrocyte-derived neurotrophic factor inhibits cervical cancer progression via regulating macrophage phenotype.
Molecular biology reports - 12 May 2024
Huang Miaomiao, Hu Jingjing, Chen Yueran, Xun Yingying, Zhang Xinru, Cao Yunxia
Abstract excerpt
BACKGROUND: Cervical cancer is a common gynecologic malignant tumor, but the critical factors affecting cervical cancer progression are still not well demonstrated. Mesencephalic astrocyte-derived neurotrophic factor (MANF) has been widely recognized as an anti-inflammatory factor to regulate macrophage polarization. In this study, the effect and mechanism of MANF on cervical cancer were preliminarily explored....
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