Article
NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells.
Cancer letters - 28 Sept 2016
Takase Nobuhisa, Koma Yu-Ichiro, Urakawa Naoki, Nishio Mari, Arai Noriaki, Akiyama Hiroaki, Shigeoka Manabu, Kakeji Yoshihiro, Yokozaki Hiroshi
Abstract excerpt
Tumor-associated macrophages (TAMs) have important roles in the angiogenesis and tumor immunosuppression of various cancers, including esophageal squamous cell carcinomas (ESCCs). To elucidate the roles of TAMs in ESCCs, we compared the gene expression profiles between human peripheral blood monocyte-derived macrophage-like cells (Macrophage_Ls) and Macrophage_Ls stimulated with conditioned medium of the TE...
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