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Article

Association of Pre-S/S and Polymerase Mutations with Acute and Chronic Hepatitis B Virus Infections in Patients from Rio de Janeiro, Brazil.

Viruses - 24 Jun 2022

de Almeida Ribeiro Camilla Rodrigues, Martinelli Katrini Guidolini, da Motta de Mello Vinícius, Spitz Natália, Araújo Oscar Rafael Carmo, Lewis-Ximenez Lia Laura, Araujo Natalia Motta, de Paula Vanessa Salete

Abstract excerpt

Several hepatitis B virus (HBV)-related factors, including the viral load, genotype, and genomic mutations, have been linked to the development of liver diseases. Therefore, in this study we aimed to investigate the influence of HBV genetic variability during acute and chronic infection phases. A real-time nested PCR was used to detect HBV DNA in all samples (acute, n = 22; chronic, n = 49). All samples were...

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Identifiers

PMID: 35891356
DOI: 10.3390/v14071375
PMCID: PMC9315576

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