Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

USP11 regulates proliferation and apoptosis of human spermatogonial stem cells via HOXC5-mediated canonical WNT/β-catenin signaling pathway

9 May 2024

Abstract excerpt

Spermatogonial stem cells (SSCs) are capable of transmitting genetic information to the next generations and they are the initial cells for spermatogenesis. Nevertheless, it remains largely unknown about key genes and signaling pathways that regulate fate determinations of human SSCs and male infertility. In this study, we explored the expression, function, and mechanism of USP11 in controlling the proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sperm and Testicular Function

Source

Identifiers

PMID: 38722330
DOI: 10.1007/s00018-024-05248-6

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

USP11 regulates proliferation and apoptosis of human spermatogonial stem cells via HOXC5-mediated canonical WNT/β-catenin signaling pathwayPMID 38722330Read ↗

Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesisSemantic proximity Read ↗

MAP4K4/JNK Signaling Pathway Stimulates Proliferation and Suppresses Apoptosis of Human Spermatogonial Stem Cells and Lower Level of MAP4K4 Is Associated with Male InfertilitySemantic proximity Read ↗

Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewalSemantic proximity Read ↗

Spermatogonial stem cells, infertility and testicular cancerSemantic proximity Read ↗

TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXLSemantic proximity Read ↗

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility RestorationSemantic proximity Read ↗

RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes.Semantic proximity Read ↗

Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradationSemantic proximity Read ↗

OIP5 Interacts with NCK2 to Mediate Human Spermatogonial Stem Cell Self-Renewal and Apoptosis through Cell Cyclins and Cycle Progression and Its Abnormality Is Correlated with Male InfertilitySemantic proximity Read ↗

PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1Semantic proximity Read ↗

SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicingSemantic proximity Read ↗

Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.