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Article

Clinicopathologic and molecular correlates to neoadjuvant chemotherapy-induced pathologic response in breast angiosarcoma.

Genes, chromosomes & cancer - 1 May 2024

Chang Hsin-Yi, Dermawan Josephine K, Kuba Maria Gabriela, Crago Aimee M, Singer Samuel, Tap William, Chi Ping, D'Angelo Sandra, Rosenbaum Evan, Antonescu Cristina R

Abstract excerpt

Both primary and secondary breast angiosarcoma (AS) are characterized by multifocal presentation and aggressive behavior. Despite multimodality therapy, local and distant relapse rates remain high. Therefore, neoadjuvant chemotherapy (NACT) is employed to improve the R0 resection rates and survival, but its benefits remain controversial. Herein, we investigate pathologic and molecular correlates to NACT-induced...

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PMID: 38722225
DOI: 10.1002/gcc.23240

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