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Article

Multiomics sequencing and immune microenvironment characteristics define three subtypes of small cell neuroendocrine carcinoma of the cervix.

The Journal of pathology - 1 Jul 2024

Pan Baoyue, Yan Shumei, Yuan Linjing, Xiang Huiling, Ju Mingxiu, Xu Shijie, Jia Weihua, Li Jundong, Zhao Qi, Zheng Min

Abstract excerpt

Small cell cervical carcinoma (SCCC) is the most common neuroendocrine tumor in the female genital tract, with an unfavorable prognosis and lacking an evidence-based therapeutic approach. Until now, the distinct subtypes and immune characteristics of SCCC combined with genome and transcriptome have not been described. We performed genomic (n = 18), HPV integration (n = 18), and transcriptomic sequencing (n = 19)...

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Identifiers

PMID: 38721894
DOI: 10.1002/path.6290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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