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Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions

30 Apr 2024

Abstract excerpt

Paxillin is a ubiquitously expressed adaptor protein integral to focal adhesions, cell motility, and apoptosis. Paxillin has also recently been implicated as a mediator of nongenomic androgen receptor (AR) signaling in prostate cancer and other cells. We sought to investigate the relationship between paxillin and AR in granulosa cells (GCs), where androgen actions, apoptosis, and focal adhesions are of known...

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PMID: 38718206
DOI: 10.1093/molehr/gaae018

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