Article
Economic Evaluation of HLA-B*15:02 Genotyping for Asian Australian Patients With Epilepsy.
JAMA dermatology - 1 Jun 2024
Gu Yaron, Shih Sophy T F, Geevasinga Nimeshan, Chan Linda, Frew John W, Sebaratnam Deshan F
Abstract excerpt
Importance: The HLA-B*15:02 allele has been associated with an increased risk of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in specific Asian populations (including Han Chinese, Malaysian, Thai, and Vietnamese individuals). While HLA-B*15:02 genotype testing in Asian populations is recommended by several international prescribing guidelines, it is not subsidized by the Medicare...
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