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Article

Effect of circ MTHFD2 on resistance to pemetrexed in gastric cancer through regulating expression of miR-124.

1 Dec 2019

Abstract excerpt

OBJECTIVE: The aim of this study was to explore the effect of circ MTHFD2 on resistance to pemetrexed (MTA) in gastric cancer by regulating the expression of micro ribonucleic acid (miR)-124. MATERIALS AND METHODS: Human gastric cancer MGC-803 cells were induced by MTA at an increasing concentration. MGC-803/MTA resistant cell model was successfully established after 5 months. The half-maximal inhibitory...

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PMID: 31841184
DOI: 10.26355/eurrev_201912_19667

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