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Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans

7 May 2024

Abstract excerpt

mRNA vaccines are likely to become widely used for the prevention of infectious diseases in the future. Nevertheless, a notable gap exists in mechanistic data, particularly concerning the potential effects of sequential mRNA immunization or preexisting immunity on the early innate immune response triggered by vaccination. In this study, healthy adults, with or without documented prior SARS-CoV-2 infection, were...

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PMID: 38716734
DOI: 10.1172/jci.insight.175401

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