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Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis

7 May 2024

Abstract excerpt

Atopic dermatitis (AD) is an inflammatory skin condition with a childhood prevalence of up to 25%. Microbial dysbiosis is characteristic of AD, with Staphylococcus aureus the most frequent pathogen associated with disease flares and increasingly implicated in disease pathogenesis. Therapeutics to mitigate the effects of S. aureus have had limited efficacy and S. aureus-associated temporal disease flares are...

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PMID: 38716729
DOI: 10.1172/jci.insight.178789

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