Article
Predicting outcome in higher-risk myelodysplastic syndrome patients treated with azacitidine.
Epigenomics - 1 Jul 2021
Bouchla Anthi, Thomopoulos Thomas P, Papageorgiou Sotirios G, Apostolopoulou Christina, Loucari Constantinos, Mpazani Efthimia, Pappa Vasiliki
Abstract excerpt
5-Azacitidine (5-AZA) is widely used for the treatment of higher-risk myelodysplastic syndromes. However, response and survival rates vary considerably, while indicated treatment duration remains undefined. For these reasons, factors determining response and survival are of major importance. Clinical, morphological, flow cytometry, cytogenetic and molecular factors are discussed in this review. Biomarkers...
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