Article
Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?
Clinical and experimental nephrology - 1 Oct 2024
Celegen Kubra, Gulhan Bora, Fidan Kibriya, Yuksel Selcuk, Yilmaz Neslihan, Yılmaz Aysun Caltik, Demircioğlu Kılıç Beltinge, Gokce Ibrahim, Kavaz Tufan Aslı, Kalyoncu Mukaddes, Nalcacıoglu Hulya, Ozlu Sare Gulfem, Kurt Sukur Eda Didem, Canpolat Nur, K Bayazit Aysun, Çomak Elif, Tabel Yılmaz, Tulpar Sebahat, Celakil Mehtap, Bek Kenan, Zeybek Cengiz, Duzova Ali, Özçakar Zeynep Birsin, Topaloglu Rezan, Soylemezoglu Oguz, Ozaltin Fatih
Abstract excerpt
BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a rare, mostly complement-mediated thrombotic microangiopathy. The majority of patients are infants. In contrast to infantile-onset aHUS, the clinical and genetic characteristics of adolescence-onset aHUS have not been sufficiently addressed to date. METHODS: A total of 28 patients (21 girls, 7 boys) who were diagnosed as aHUS between the ages of ≥10 years...
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