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Article

Pleural effusion supernatant: a reliable resource for cell-free DNA in molecular testing of lung cancer.

Journal of the American Society of Cytopathology - 1 Jan 2024

Thakur Shilpi, Rathor Amber, Jain Surabhi, Nambirajan Aruna, Khurana Sachin, Malik Prabhat Singh, Jain Deepali

Abstract excerpt

INTRODUCTION: DNA extracted from malignant pleural effusion (PE) sediments is the traditional source of tumor DNA for predictive biomarker molecular testing (MT). Few recent studies have proposed the utility of cell-free DNA (cfDNA) extracted from effusion cytology centrifuged supernatants (CCS) in MT. The aim of this study was to assess the feasibility and utility of molecular testing on cfDNA extracted from PE...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circulating Tumor DNA

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Source

Identifiers

PMID: 38704351
DOI: 10.1016/j.jasc.2024.03.006

Genes

CCS
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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